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Cleveland Guardians vs Houston Astros — Polymarket odds & smart money picks · MLB · Polyranks
MLB
Cleveland Guardians
vs
Houston Astros
Head-to-head:
Cleveland Guardians 1–2 Houston Astros
· of last 3 meetings
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Recent meetings
Houston Astros
at
Cleveland Guardians
Apr 22, 2026
2 – 0
Houston Astros
at
Cleveland Guardians
Apr 21, 2026
5 – 8
Houston Astros
at
Cleveland Guardians
Apr 20, 2026
9 – 2